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The analysis of Chromosome Mapping stained chromosomes is the main activity of the finalise called cytogenetics. deoxyribonucleic acid stains illicit a reproducible banding example on chromosomes Quinacrine and Giemsa: DNA dye- chromosome specific pattern Has allowed to for occasion of regions in a chromosome p and q arms and different regions Quinacrine, a chemic relative of the antimalarial drug quinine, was wizard of the kickoff of these more discriminating reagents. Chromosomes that ca-ca been stained with mepacrine learn a characteristic pattern of bright bands on a darker background. However, because quinacrine is a fluorescent compound, the bands appear alone when the chromosomes atomic number 18 loose to ultraviolet (UV) light. Ultraviolet irradiation causes some of the quinacrine molecules that have inserted into the chromosome to emit energy. Excellent nonfluorescent staining techniques have withal been developed. The close to popular of the se uses Giemsa stain, a mixture of dyes named after its inventor, Gustav Giemsa. give care quinacrine, Giemsa creates a reproducible pattern of bands on each chromosome. 4 ^^^^^Chromosome painting. Probesmade from human DNA have been applied to aspread of human chromosomes.

for each one probe hasbeen designate with a dye that fluoresces a differentcolor ( rap or bright greens) to chance on where Fragments are a specific complementary color sequence .. pink is the centromere, green is the sequence specific to three chromosomes DNA sequences complementary to these probesare placed in the chromosomes. T he pink probetargets DNA in the centromere o! f both chromosome,whereas the bright green probe targets DNA in only three pairs of chromosomes. Treat mitotic spreads with DNA fragments labelled with flurochromes-Any of a radical of fluorescent dyes used to stain biological specimens. Chromosome Variation A karyotype shows the duplicated chromosomes of a cell arranged for cytogenetic analysis (46 xx Euploid- one set of chromosomes Polyploid-...If you want to get a intact essay, ordinate it on our website: OrderCustomPaper.com

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